| Ultrastructural change of the Muller cell in the culture of sensory retina. |
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Byung Joo Song, Myung Kyoo Ko, Joon Kiu Choe |
1Department of Ophthalmology, Hanil General Hospital, Seoul, Korea.
2Department of Ophthalmology, College of Medicine, Hanyang University, Seoul, Korea. |
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| Abstract |
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This study was performed to investigate the sequential changes of the retinal tissue in tissue culture condition. The human sensory retinal tissues were cultured for up to 2 weeks and 4 weeks, respectively. The initial changes showed the separation of the intercellular space and the consequent widening of the intercellular space with prolapse of cytoplasmic processes into the widened intercellular space. The internal limiting membrane was also separated from the inner retina, which led to the prolapse of the cytoplasm of the Muller cell. The growth of the Muller cell was most prominent during the 4-weeks' tissue culture period. These findings suggest that the Muller cell might contribute to the formation of cellular membrane in case of the defect of the internal limiting membrane in several pathologic conditions. |
| Key Words:
Muller cell;preretinal membrane;sensory retina;tissue culture |
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