Korean J Ophthalmol > Volume 6(2); 1992 > Article
Korean Journal of Ophthalmology 1992;6(2):100-104.
DOI: https://doi.org/10.3341/kjo.1992.6.2.100    Published online December 30, 1992.
Positive family history of glaucoma is a risk factor for increased IOP rather than glaucomatous optic nerve damage (POAG vs OH vs normal control).
Ki Bang Uhm, Dong H. Shin
1Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
2Kresge Eye Institute, School of Medicine, Wayne State University, Detroit, Michigan, USA.
To elucidate the family history of glaucoma (FHG) as a risk factor for ocular hypertension(OH) vs glaucomatous optic nerve damage, we reviewed the clinical records of 361 primary open-angle glaucoma(POAG) patients, 178 OH subjects, and 927 normal controls randomly selected from an urban medical center eye clinic. The prevalence of a positive FHG was 27% in the POAG patients, 47% in the OH subjects, and 11% in the normal controls. Whereas a positive FHG was a significant risk factor for both OH and glaucoma compared to normal control subjects (OR = 7.56, 95% CI: 5.27-10.85, P < .0001 for OH; OR = 3.15, 95% CI: 2.31-4.31, P < .0001), it was a risk factor more significantly for OH than for glaucoma being significantly more prevalent in OH than in POAG (OR = 2.40, 95% CI: 1.65-3.49, P < .0001). These results suggest the importance of additional risk factors other than IOP for glaucomatous optic nerve damage.
Key Words: family history of glaucoma;risk factors;primary open-angle glaucoma;ocular hypertension
METRICS Graph View
  • 3 Crossref
  • 9 Scopus
  • 1,103 View
  • 19 Download
Related articles

Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next