Korean J Ophthalmol > Volume 7(1); 1993 > Article
Korean Journal of Ophthalmology 1993;7(1):28-33.
DOI: https://doi.org/10.3341/kjo.1993.7.1.28    Published online June 30, 1993.
Effect of apraclonidine hydrochloride on the attack of Posner-Schlossman syndrome.
Chul Hong, Ki Yung Song
Glaucoma Service, Dr. Hong's Eye Clinic, Seoul, Korea.
The intraocular pressure (IOP) of glaucomatocyclitic crisis with the attack fell 50.3%, from 37.8 +/- 8.2 mmHg to 18.8 +/- 4.8 mmHg, 4 hours after instillation of 1% apraclonidine. Glaucomatocyclitic crisis showed a more significant hypotensive response to 1% apraclonidine than primary open-angle glaucoma (24.8%, from 43. 1 +/- 8.1 mmHg to 32.4 +/- 7.5 mmHg after 4 hours). The intraocular pressure decrease percentage was similar regardless of the initial level of intraocular pressure. Clinically significant changes in mean systolic and diastolic blood pressures, were not observed, however, a mild decrease in the pulse rate was noted. And the local mydriatic effect on the pupillary diameter was significant. Apraclonidine, 1% might be newly indicated to control the IOP rise of glaucomatocyclitic crisis. Further studies on the possible mechanism of the prostaglandin mediated hypotensive effect of 1% apraclonidine are suggested.
Key Words: apraclonidine;glaucomatocyclitic crisis;intraocular pressure;primaryopen-angle glaucoma

Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next