Korean J Ophthalmol > Epub ahead of print
DOI: https://doi.org/10.3341/kjo.2025.0171    [Epub ahead of print]
Published online December 22, 2025.
Optimal Time for Stabilization of Anterior Corneal Keratometry after Primary Pterygium Excision Adjusted for Horizontal Invasion Length
Seunghwan Kim1, Seung Hyeun Lee2, Kyoung Woo Kim1
1Department of Ophthalmology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
2Department of Ophthalmology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Gwangmyeong, Korea
Correspondence:  Kyoung Woo Kim, Tel: 82-2-6299-1689, Fax: 82-2-825-1666, 
Email: kkanssa@cau.ac.kr
Received: 10 November 2025   • Revised: 4 December 2025   • Accepted: 12 December 2025
Abstract
Purpose
To determine the corneal stabilization timeline after pterygium excision adjusted for horizontal invasion length (HIL).
Methods
In this single-center retrospective cohort, we analyzed 88 eyes of 80 patients with nasal or temporal primary pterygium who underwent excision and perioperative evaluation with anterior segment swept-source OCT (AS SS-OCT, Anterion®). Anterior simulated mean keratometry (SimKmean; 3-mm ring) and HIL were measured on AS SS-OCT. Keratometric stabilization was assessed at postoperative cutoffs of 8, 12, 16, 20, and 24 weeks using analysis of covariance (ANCOVA) with HIL as a covariate. Subgroup analysis was performed after stratifying by the median HIL (3.82 mm).
Results
Mean anterior SimKmean increased from 42.95 ± 1.79 D preoperatively to 43.73 ± 1.53 D postoperatively (P < 0.001). Preoperative HIL correlated positively with the perioperative SimKmean change (r = 0.728 and P < 0.001). While postoperative duration showed no significant unadjusted correlation with keratometric change (r = −0.133 and P = 0.218), partial correlation controlling for HIL was negative (r = −0.248 and P = 0.021), indicating diminishing change over time after severity adjustment. ANCOVA demonstrated significant stabilization at 16 weeks (P = 0.036). In the HIL ≥ 3.82 mm subgroup, SimKmean change was greater before 20 weeks than after 20 weeks (1.73 ± 1.59 D vs 0.59 ± 0.74 D; P = 0.030), whereas no significant time-point differences were found for HIL < 3.82 mm.
Conclusion
Corneal keratometric stabilization after pterygium excision depends on preoperative HIL. A minimum of 16 weeks is recommended before cataract surgery planning, with at least 20 weeks for eyes with HIL ≥ 3.82 mm.
Key Words: Horizontal invasion length; Keratometry; OCT; Pterygium
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