Korean J Ophthalmol > Volume 39(3); 2025 > Article
Korean Journal of Ophthalmology 2025;39(3):231-240.
DOI: https://doi.org/10.3341/kjo.2025.0016    Published online May 7, 2025.
Assessment of Tonometry Methods in Keratoconic Eyes Following Intracorneal Ring Segments Implantation: A Comparative Study
Siamak Zarei-Ghanavati1, Seyed Mehdi Tabatabaei2, Samaneh Gholamhoseinpour-Omran1, Hamed Hosseinikhah-Manshadi1,2, Saeed Banan1, Mehdi Aminizade2, Kosar Esmaili2, Ebrahim Azaripour2,3
1Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
3Eye Research Center, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran
Correspondence:  Seyed Mehdi Tabatabaei, Tel: 98-9122307414, Fax: 98-2155410520, 
Email: Meh.Tabatabaei@gmail.com
Received: 4 February 2025   • Revised: 18 April 2025   • Accepted: 6 May 2025
Abstract
Purpose
To compare intraocular pressure (IOP) readings from corneas with intracorneal corneal ring segments (ICRS) using various methods, including Goldmann applanation tonometry (GAT), Tonopen, corneal-compensated IOP from the Ocular Response Analyzer (ORA), and biomechanically corrected IOP from the Corneal Visualization Scheimpflug Technology (Corvis ST).
Methods
This cross-sectional observational study included participants who had undergone ICRS implantation with KeraRing at least 3 months before the study. The mean IOP recorded by different instruments was compared using analysis of variance. Agreement among the methods was assessed with Bland-Altman plots.
Results
A total of 54 eyes from 27 participants were enrolled. The mean IOP measured by Tonopen was significantly lower in the center compared to the peripheral quadrants (p < 0.001). IOP measured by GAT was significantly lower than that measured by Tonopen (13.02 ± 2.31 mmHg vs. 14.50 ± 2.91 mmHg, p = 0.021). There were no significant differences between the IOP measurements provided by Tonopen, ORA, and Corvis ST. The corneal-compensated IOP from ORA and biomechanically corrected IOP from Corvis ST had the highest correlation, with a weak intraclass correlation coefficient of 0.38.
Conclusions
IOP measurements using Tonopen were significantly lower in the central 5-mm zone compared to other quadrants. GAT measurements were significantly lower than those from Tonopen. Different measurement tools did not show a strong correlation. Corvis ST (biomechanically corrected IOP) tended to present lower readings at higher IOP levels in eyes with ICRS.
Key Words: Biomechanically corrected intraocular pressure, Corneal-compensated intraocular pressure, Intracorneal ring segments, Intraocular pressure, Keratoconus


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