Korean J Ophthalmol > Epub ahead of print
DOI: https://doi.org/10.3341/kjo.2023.0129    [Epub ahead of print]
Published online April 8, 2024.
Self-reported Findings of the Korean Intermittent Exotropia Multicenter Study Questionnaire
Hee Kyung Yang1, Shin Hae Park2, Haeng-Jin Lee3, Sook-Young Kim4, Hyo Jung Gye5, So Young Kim6, Sun Young Shin2, Key Hwan Lim7, the Korean Association of Pediatric Ophthalmology and Strabismus (KAPOS)
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
2Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
3Department of Ophthalmology, Jeonbuk National University College of Medicine, Jeonju, Korea
4Department of Ophthalmology, School of Medicine, Daegu Catholic University, Daegu, Korea
5Department of Ophthalmology, Nune eye hospital, Seoul, Korea
6Department of Ophthalmology, Soonchunhyang University Cheonan Hospital, Cheonan, Korea
7Department of Ophthalmology, Ewha Womans University College of Medicine, Seoul, Korea
Correspondence:  Key Hwan Lim, Tel: +82-2-2650-5659, Fax: +82-2-2654-4334, 
Email: limkh@ewha.ac.kr
Received: 26 November 2023   • Revised: 7 February 2024   • Accepted: 20 March 2024
To determine subjective symptoms and medical history of patients with intermittent exotropia in a large study population.
The Korean Intermittent Exotropia Multicenter Study (KIEMS) is a nationwide, observational, cross-sectional, multicenter study conducted by the Korean Association for Pediatric Ophthalmology and Strabismus (KAPOS) including 5385 patients with intermittent exotropia. Subjective symptoms and medical history of patients with intermittent exotropia were extracted by a comprehensive survey based on a self-administered questionnaire according to the study protocol of the KIEMS.
The mean age of symptom onset was 5.5 years of age. The most common symptom reported in patients with intermittent exotropia was photophobia (52.1%), followed by diplopia at near (7.3%) and distance fixation (6.2%). Preterm birth was found in 8.8%, and 4.1% had perinatal complications. A family history of strabismus was present in 14.9%, and 5.5% of patients had a family member who underwent strabismus surgery.
The KIEMS is one of the largest clinical studies on intermittent exotropia. Intermittent exotropia frequently caused photophobia and diplopia, and patients with a family history was not uncommon.
Key Words: Exotropia, Multicenter study, Questionnaire, Symptom

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