Korean J Ophthalmol > Epub ahead of print
DOI: https://doi.org/10.3341/kjo.2023.0116    [Epub ahead of print]
Published online April 8, 2024.
Visual Outcome of Non-traumatic Dense Vitreous Hemorrhage in Patients without Diabetes: Single Center Case Series
Yuri Lee, Jae Suk Kim
Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
Correspondence:  Jae Suk Kim, Tel: 82-2-950-1096, Fax: 82-2-950-1930, 
Email: s5535@paik.ac.kr
Received: 31 October 2023   • Revised: 12 March 2024   • Accepted: 19 March 2024
Abstract
Purpose
Dense vitreous hemorrhage is a vision-threatening disease with varied clinical manifestations. Herein, we aimed to evaluate its causes and outcomes in patients without diabetes.
Methods
A retrospective cohort including 60 eyes from 60 patients with an initial diagnosis of non-traumatic fundus-obscuring dense vitreous hemorrhages and without diabetes was recruited. The relevant medical records from January 2013 to December 2019 were reviewed and analyzed. We classified patients into the following four groups, depending on the underlying cause of dense vitreous hemorrhage: eight cases in the age-related macular degeneration (AMD) group, four cases in the posterior vitreous detachment group, 20 cases in the Tear group, and 28 cases in the Vascular group.
Results
The most common cause of dense vitreous hemorrhage was retinal vascular obstructive disease (46.7%); the AMD group showed the worst prognosis. The extent of best corrected visual acuity change was significantly better in patients who underwent vitrectomy compared to those receiving conservative treatment; best corrected visual acuity change (logMAR) was 1.62±0.57 and 1.06±0.88 in the surgical and non-surgical groups, respectively (p=0.007, Student t-test).
Conclusions
Retinal vascular disease is the most common cause of vitreous hemorrhages, and surgical treatments have a better visual outcome than non-surgical treatments.
Key Words: Age-related macular degeneration, Visual acuity, Vitreous hemorrhage
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